MCB/EEB 371 - Spring 2002

This is the tentative list of topics for MCB371. Student presentations are scheduled to last about 20 minutes. Chapters refer to the book from Wen-Hsiung Li "Molecular Evolution" (Sinauer, http://www.sinauer.com/Titles/frlimol.htm).

Date Topic Presenter
Feb 11 Sequence Alignment
(Chapter 4)
Lindsay Carubia
Feb 18 Dynamics of genes in populations, random drift, fitness, effect of population size
(Chapter 2)
Kamolwan Thirangoon
Feb 25 Models of Substitution: Nucleotides
(Chapter 3)
Jeff Gawronski

Models of Substitution: Amino Acids
March 4 Among Site Rate Variation (Chapter 3) Reshma Shial
March 4 Estimating number of substitutions (Chapter4) William Smith
March 11 Distance Analyses: Neighbor-Joining and UPGMA
(Chapter 5)
Ryan Novak
March 11 Distance Analyses: Minimum evolution, Fitch-Margoliash
(Chapter 5)
Gianni Ferreri
March 11 Principles of Parsimony Analyses
(Chapter 5)
Tom Mullen

Maximum Likelihood Analyses
(Chapter 5)


Non-parametric Bootstrapping
(Chapter 5)

March 25 Parametric Bootstrapping Tao Sun

Bayesian Inference
April 8 Examples: Origin of Eukaryotes (or/and other Examples) (Chapter 6) Jim Macione

Rates and patterns of substitutions
(Chapter 7)

April 15 Molecular Clocks
(Chapter 8)
Pascal Lapierre

Gene duplication, Transposition and horizontal transfer
(Chapter 10,11,12)